Xenopus - From Basic Biology to Disease Models in the Genomic Era

This book focuses on the amphibian, Xenopus, one of the most commonly used model animals in the biological sciences. Over the past 50 years the use of Xenopus has made possible many fundamental contributions to our knowledge in cell biology, developmental biology, molecular biology, and neurobiology. In recent years, with the completion of the genome sequence of the main two species and the application of genome editing techniques, Xenopus has emerged as a powerful system to study fundamental disease mechanisms and test treatment possibilities. Xenopus has proven to be an essential vertebrate model system for understanding fundamental cell and developmental biological processes; for applying fundamental knowledge to pathological processes; for deciphering the function of human disease genes; and for understanding genome evolution.
Key Features

[*]Provides historical context of the contributions of the model system
[*]Contributions from an international team of leading scholars
[*]Topics span cell biology, developmental biology, genomics and evolution
[*]Includes recent experimental advances
[*]Richly illustrated with diagrams and color images

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