Sherlock Holmes vs. Dracula by Loren D. Estleman

The year is 1890. A ship is discovered adrift off the English coast, its crew missing, its murdered captain lashed to the wheel, and its only passenger is a sinister black dog. This impenetrable mystery is clearly a case for the inimitable Sherlock Holmes, but for the first time in his illustrious career the great detective is baffled. Clearly the crew have been murdered and dumped overboard, but what can account for the captain's expression of imponderable terror and his acute loss of blood, or the ship's strange cargo-fifty boxes of earth?
The game is afoot, and Sherlock Holmes, aided as ever by the faithful Dr. Watson, finds himself on the trail of no mortal enemy, but the arch-vampire himself-Count Dracula...
From the impalement of the "Bloofer Lady" to the abduction of Watson's beloved wife, Mary, from the death of a harmless prostitute to a terrifying conclusion on a lonely beach, this unique case is at once a glorious celebration of two of the most famous literary genres, a riveting thriller with sensational climaxes, and a tale guaranteed to delight all Holmes and Dracula lovers everywhere.