The House at the End of the World by Dean Koontz

Soon no one on Earth will have a place to hide in this novel about fears known and unknown by #1 New York Times bestselling master of suspense Dean Koontz.
In retreat from a devastating loss and crushing injustice, Katie lives alone in a fortresslike stone house on Jacob's Ladder island. Once a rising star in the art world, she finds refuge in her painting.
The neighboring island of Ringrock houses a secret: a government research facility. And now two agents have arrived on Jacob's Ladder in search of someone-or something-they refuse to identify. Although an air of menace hangs over these men, an infinitely greater threat has arrived, one so strange even the island animals are in a state of high alarm.
Katie soon finds herself in an epic and terrifying battle with a mysterious enemy. But Katie's not alone after all: a brave young girl appears out of the violent squall. As Katie and her companion struggle across a dark and eerie landscape, against them is an omnipresent terror that could bring about the end of the world.

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