ENHANZE Drug Delivery Technology
Lun Dic 26, 2022 9:36 pm
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pdf | 10.41 MB | English | Isbn: 3318070769 | Author: David W. Kang and Renee Tannenbaum | Year: 2022
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Description:
Category:Pharmacology'ENHANZE drug delivery technology: Advancing subcutaneous drug delivery using recombinant human hyaluronidase PH20' provides readers with in-depth information on the potential benefits and challenges of subcutaneous (SC) drug delivery, the biology of hyaluronan and hyaluronidases in the SC space, and a comprehensive overview on the history of hyaluronidases and the development of recombinant human hyaluronidase PH20 (rHuPH20). Current applications of rHuPH20 as well as approved biotherapeutics utilizing HuPH20-facilitated SC drug delivery are summarized, and the underlying non-clinical and clinical development approaches are introduced as a basis for future application to biologics in various disease areas. Table of Contents: • Introduction to subcutaneous drug delivery • Biology of hyaluronan and hyaluronidases in the subcutaneous space • History of hyaluronidases and development of rHuPH20 • The ENHANZE platform: Clinical applications of a subcutaneous drug delivery technology • Application of ENHANZE drug delivery technology: Development of currently marketed products
https://rapidgator.net/file/46185d3df98ce3ed551ba696a3c5e0f8/
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